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A method for determination of
personal 1,3-butadiene exposure.
Clean air is an important
objective for Swedish environmental policy, and one of the aims is to reduce the
levels of carcinogenic compounds in general air. 1,3-butadiene (BD) is probably
carcinogenic to humans (IARC 2A), and according to the US EPA is one of the top
three chemicals contributing to cancer in the general population. Population
exposure to BD in Sweden is unknown and also data from stationary measurements
in urban or rural background are sparse. At present no method suitable for
personal BD exposure measurements has been validated for low-level exposure in
the general population.
The aim of this project is to
optimize and validate a method for personal diffusive sampling possible to use
in the general population, with a sampling time of up to two weeks. In parallel
we will validate a commercially available diffusive sampler (3M 3500) and
diffusive samplers with various other carbon absorbents (active and graphitized).
In all cases the adsorbent will be thermally desorbed and analysed by gas
chromatography. Validation will be performed according to the recommendations in
CEN TC264/WG11 ‘Diffusive samplers’, required by the EU in the ‘Ambient
air’-directive.
The method will be used in
projects where BD is sampled in the general population.
| Participants: |
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| Lars Barregård |
Occupational and
Environmental Medicine, Göteborg University |
| Göran Ljungqvist |
Occupational and
Environmental Medicine, Göteborg University |
| Olof Johansson |
Occupational and
Environmental Medicine, Göteborg University |
| Gerd Sällsten |
Occupational and
Environmental Medicine, Göteborg University |
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Progress
report 2003 |
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